000			01846nam a22002057a 4500
005			20240117161606.0
008			240116b ||||| |||| 00| 0 eng d
022			_a0021-9584
100			_aHilts, Adrian R.
245			_aImproved Yields of Dichlorobis(triphenylphosphine)nickel(II) and Related Compounds by Employing Triethyl Orthoformate as an In Situ Dehydrating Agent _b: Rational Improvement of a Classic Undergraduate Inorganic Synthesis (Journal Article)
260			_aWashington DC _b: American Chemical Society _c, 2023
300			_a4119–4121p.
440			_aJournal of Chemical Society _v, Volume 100: Number 10, October 2023
505			_a***______{For Hard Copy, Please visit Library.}________***
520			_aAbstract: The addition of a small excess of triethyl orthoformate to an alcoholic mixture of NiCl2·6H2O and triphenylphosphine (PPh3) results in an increase in the typical isolated yield of [NiCl2(PPh3)2] from below 50% to over 85%. The impact of water when present in the reaction medium in this system is discussed, and results from the application of the same synthetic approach to the syntheses of [NiBr2(PPh3)2], [NiCl2(dppe)], and [NiBr2(dppe)] are presented. A simple synthesis of NiCl2·2H2O by the dehydration of NiCl2·6H2O at 80 °C can be performed as an optional step to decrease the quantity of triethyl orthoformate required for the preparation of [NiCl2(PPh3)2] and/or [NiCl2(dppe)]. The experiments are flexible and accommodate a variety of laboratory schedules and student skill levels. Each synthesis can be readily completed within a 3 h laboratory period.
650			_aInorganic Chemistry| Laboratory Instruction| Hands-On Learning/Manipulatives| Coordination Compounds| Synthesis
700			_aCooke, Jason
856			_uhttps://doi.org/10.1021/acs.jchemed.3c00637
942			_cPER
999			_c45364 _d45363