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022 _a0021-9584
037 _bRIEBPL Library
082 _a540.7
100 _aDaniel L. Silverio, Matthew J. Mistretta, and Scott P. Buzzolani
245 _aTo the Literature and Beyond: Teaching Advanced Organic Chemistry at a Primarily Undergraduate Institution
_b(Journal Article)
_c
260 _aWashington, United States
_b:American Chemical Society
_c,January 10, 2023
300 _a 143–149p.
490 _aAmerican Chemical Society, Volume 100, Issue 1
505 _a***______{For Hard Copy, Please visit Library.}________***
520 _aAbstract- Offering an advanced organic chemistry course at a primarily undergraduate institution poses a challenge of condensing graduate organic synthesis into one course. This course was designed so students choose and read recent total synthesis papers from the literature in lieu of relying on a textbook or other pre-existing course materials. Following the reading, students are required to propose a reasonable arrow-pushing mechanism for each step in the paper. The professor guides students on how to develop the ability to use resources (e.g., the primary literature, books, search engines, etc.) to propose mechanisms for reactions that are new to the students. In-class group work is implemented to promote active learning of complex topics. All mechanism proposals are presented to the entire class so that students become competent at communicating complex topics to others. Students not only learn many new reagents, reactions, and mechanisms relevant to modern organic synthesis but more importantly become proficient in finding detailed information on unfamiliar topics, a skill valuable to any scholar. As the course does not require the creation of materials such as problem sets or lecture notes, it can be taught with minimal preparation and work during the week by an instructor holding a PhD in synthetic organic chemistry or a closely related field.
650 _aUpper-Division Undergraduate
650 _aPrimarily Undergraduate
650 _aInstitution Organic Chemistry
650 _a Literature-Based Courses
650 _aCooperative Learning Advanced Organic Chemistry
650 _a In-Depth Chemistry Courses
856 _u https://doi.org/10.1021/acs.jchemed.2c00479
942 _cPER
999 _c44658
_d44657