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022 _a0021-9584
037 _bRIEBPL Library
082 _a540.7
100 _aRafael Amador-Rodríguez et al ...
245 _a Explanatory Models Derived from Context-Based Teaching: An Investigation in Undergraduate Chemistry Education
_b (Journal Article)
260 _aUSA
_b:American Chemical Society
_c,May 2023
300 _a 1777-1787p.
490 _aAmerican Chemical Society, Volume 100, Issue 5
505 _a***______{For Hard Copy, Please visit Library.}________***
520 _aAbstract- This research aimed to use students’ modeling processes as a means of scientific inquiry. Students constructed models to explain the interactions between felodipine R and S and protein. The approach encouraged active student participation in molecular interaction modeling and offered students a “model-based teaching” experience for developing explanations of chemical phenomena. The concept is built on four structural concepts in chemistry─molecular interactions, Gibbs free energy, chemical equilibria, and optical isomerism. This framework enabled the examination of medical students’ ability to integrate general chemistry for developing models that can explain drug interactions. This proposal is part of a research cycle using design-based research for a qualitative methodology centered on modeling. This research provides evidence that constructivist teaching is possible as a model-based intervention in the classrooms, measured in a medical training context, allowing students to develop, evaluate, and constantly revise their chemical understanding.
650 _aMolecular Recognition
650 _aChemical Education Research
650 _aFirst-Year Undergraduate/General
856 _u https://doi.org/10.1021/acs.jchemed.2c01212
942 _cPER
999 _c44549
_d44548