: Rational Improvement of a Classic Undergraduate Inorganic Synthesis (Journal Article) Hilts, Adrian R. creator Cooke, Jason text Washington DC : American Chemical Society , 2023 monographic eng

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4119–4121p. Abstract: The addition of a small excess of triethyl orthoformate to an alcoholic mixture of NiCl2·6H2O and triphenylphosphine (PPh3) results in an increase in the typical isolated yield of [NiCl2(PPh3)2] from below 50% to over 85%. The impact of water when present in the reaction medium in this system is discussed, and results from the application of the same synthetic approach to the syntheses of [NiBr2(PPh3)2], [NiCl2(dppe)], and [NiBr2(dppe)] are presented. A simple synthesis of NiCl2·2H2O by the dehydration of NiCl2·6H2O at 80 °C can be performed as an optional step to decrease the quantity of triethyl orthoformate required for the preparation of [NiCl2(PPh3)2] and/or [NiCl2(dppe)]. The experiments are flexible and accommodate a variety of laboratory schedules and student skill levels. Each synthesis can be readily completed within a 3 h laboratory period. ***______{For Hard Copy, Please visit Library.}________*** Inorganic Chemistry| Laboratory Instruction| Hands-On Learning/Manipulatives| Coordination Compounds| Synthesis 0021-9584 https://doi.org/10.1021/acs.jchemed.3c00637 https://doi.org/10.1021/acs.jchemed.3c00637 240116 20240117161606.0