01846nam a22002057a 4500 20240117161606.0 240116b ||||| |||| 00| 0 eng d 0021-9584 Hilts, Adrian R. Improved Yields of Dichlorobis(triphenylphosphine)nickel(II) and Related Compounds by Employing Triethyl Orthoformate as an In Situ Dehydrating Agent : Rational Improvement of a Classic Undergraduate Inorganic Synthesis (Journal Article) Washington DC : American Chemical Society , 2023 4119–4121p. Journal of Chemical Society , Volume 100: Number 10, October 2023 ***______{For Hard Copy, Please visit Library.}________*** Abstract: The addition of a small excess of triethyl orthoformate to an alcoholic mixture of NiCl2·6H2O and triphenylphosphine (PPh3) results in an increase in the typical isolated yield of [NiCl2(PPh3)2] from below 50% to over 85%. The impact of water when present in the reaction medium in this system is discussed, and results from the application of the same synthetic approach to the syntheses of [NiBr2(PPh3)2], [NiCl2(dppe)], and [NiBr2(dppe)] are presented. A simple synthesis of NiCl2·2H2O by the dehydration of NiCl2·6H2O at 80 °C can be performed as an optional step to decrease the quantity of triethyl orthoformate required for the preparation of [NiCl2(PPh3)2] and/or [NiCl2(dppe)]. The experiments are flexible and accommodate a variety of laboratory schedules and student skill levels. Each synthesis can be readily completed within a 3 h laboratory period. Inorganic Chemistry| Laboratory Instruction| Hands-On Learning/Manipulatives| Coordination Compounds| Synthesis Cooke, Jason https://doi.org/10.1021/acs.jchemed.3c00637 PER 0 0 0 0 RIEBPL RIEBPL 2024-01-17 0 2024-01-17 00:00:00 2024-01-17 PER 45364 45363