(Journal Article) Alexander J et al ... creator text USA :American Chemical Society August 2023 monographic eng

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3025-3028 P. Abstract In this paper, we present a concise and technique-heavy route to the synthesis of dimedone for a second-year organic chemistry curriculum. Our preparation of dimedone guides students through a Michael addition followed by a Dieckmann cyclization, basic ester hydrolysis, and thermal decarboxylation, while allowing time for mechanistic discussion and analysis of the product. The wide variety of techniques covered led this to be a pedagogically diverse experiment. This task is thoroughly tested and suitable for a 6 hour laboratory class (with a 1 hour lunch break) or two 3 hour stand-alone sessions. ***______{For Hard Copy, Please visit Library.}________*** Synthesis Equilibrium Reactions NMR Spectroscopy Hands-On Learning/Manipulatives Organic Chemistry Laboratory Instruction Second-Year Undergraduate Upper-Division Undergraduate 540.7 0021-9584 RIEBPL Library https://pubs.acs.org/doi/epdf/10.1021/acs.jchemed.3c00069 https://pubs.acs.org/doi/epdf/10.1021/acs.jchemed.3c00069 231020 20231116101256.0