Alexander J  et al ... <br/><br/>
Updating Dimedone─The Humble Hero of the Organic Laboratory   (Journal Article) 

 - USA  :American Chemical Society  August 2023 
 - 3025-3028  P. 
 - American Chemical Society, Volume 100, Issue 8 .
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<br/><br/> Abstract<br/> <br/>In this paper, we present a concise and technique-heavy route to the synthesis of dimedone for a second-year organic chemistry curriculum. Our preparation of dimedone guides students through a Michael addition followed by a Dieckmann cyclization, basic ester hydrolysis, and thermal decarboxylation, while allowing time for mechanistic discussion and analysis of the product. The wide variety of techniques covered led this to be a pedagogically diverse experiment. This task is thoroughly tested and suitable for a 6 hour laboratory class (with a 1 hour lunch break) or two 3 hour stand-alone sessions.<br/><br/> 
<br/><br/><label>ISSN: </label>0021-9584 
<br/><br/><label>Source: </label> RIEBPL Library 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Synthesis <br/>Equilibrium Reactions NMR Spectroscopy Hands-On Learning/Manipulatives <br/>Organic Chemistry Laboratory <br/>Instruction Second-Year Undergraduate <br/>Upper-Division Undergraduate
<br/><br/><label>Dewey Class. No.: </label>540.7