Bru, Francis creator Vanden Broeck, Sofie M. P. | Pisanò, Gianmarco | Buysser, Klaartje De | Cazin, Catherine S. J. text Washington DC :American Chemical Society ,2023 monographic eng

print

2359-2366p. Abstract: The implementation of a laboratory exercise in an undergraduate chemistry course, where students perform a comparison of three different synthetic methods toward [Cu(Cl)(IPr)]-complexes (IPr = N,N′-bis(2,6-diisopropylphenyl)imidazol-2-ylidene), is described. The students are introduced to the continuous improvement of reactions in terms of green chemistry and are provided a taste of mechanochemistry as a synthetic methodology. The direct comparison of three methods leading to the copper complexes provides an opportunity to teach green chemistry metrics including atom economy, environmental factor, mass intensity, reaction mass efficiency, and optimum efficiency, as well as Green Star; and challenges them to question the use of solvents in chemical syntheses. ***______{For Hard Copy, Please visit Library.}________*** Graduate Education| Research | Organometallic Chemistry | Hands-on Learning| Green Chemistry| Synthesis| Catalysis 0021-9584 https://pubs.acs.org/doi/10.1021/acs.jchemed.2c01134 https://pubs.acs.org/doi/10.1021/acs.jchemed.2c01134 231027 20231027120048.0