01739nam a22002057a 4500 20231027120048.0 231027b ||||| |||| 00| 0 eng d 0021-9584 Bru, Francis Learning Green Chemistry Principles by Comparing Three Synthetic Routes to a Copper-NHC (NHC = N-heterocyclic carbene) Complex (Journal Article) Washington DC :American Chemical Society ,2023 2359-2366p. Journal of Chemical Society , Volume 100: Number 6, June 2023 ***______{For Hard Copy, Please visit Library.}________*** Abstract: The implementation of a laboratory exercise in an undergraduate chemistry course, where students perform a comparison of three different synthetic methods toward [Cu(Cl)(IPr)]-complexes (IPr = N,N′-bis(2,6-diisopropylphenyl)imidazol-2-ylidene), is described. The students are introduced to the continuous improvement of reactions in terms of green chemistry and are provided a taste of mechanochemistry as a synthetic methodology. The direct comparison of three methods leading to the copper complexes provides an opportunity to teach green chemistry metrics including atom economy, environmental factor, mass intensity, reaction mass efficiency, and optimum efficiency, as well as Green Star; and challenges them to question the use of solvents in chemical syntheses. Graduate Education| Research | Organometallic Chemistry | Hands-on Learning| Green Chemistry| Synthesis| Catalysis Vanden Broeck, Sofie M. P. | Pisanò, Gianmarco | Buysser, Klaartje De | Cazin, Catherine S. J. https://pubs.acs.org/doi/10.1021/acs.jchemed.2c01134 PER 0 0 0 0 RIEBPL RIEBPL 2023-10-27 0 2023-10-27 00:00:00 2023-10-27 PER 44620 44619