An Experiment for Undergraduate Analytical Chemistry Laboratory (Journal Article) Michaela Kuchynka et al... creator text USA :American Chemical Society ,May 2023 monographic eng

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1973–1979p. Abstract- A new experiment using laser ablation with inductively coupled plasma mass spectrometry (LA-ICP-MS) was designed for chemistry undergraduate students. While most analytical methods only provide information on the amount of the analyte, LA-ICP-MS allows extra information on the distribution of the element in the sample. Because it achieves excellent limits of detection (sub μg·g–1) and high spatial resolution (micrometer scale), it is a powerful technique for imaging any sample. A thin section of mouse tissue was used as a model sample to demonstrate these abilities. The student’s task was to determine the distribution of the essential elements Zn, Cu, and Pt (Pt introduced into the tumor tissue from the cytostatic drug (cis Pt)) and quantify their amount. ***______{For Hard Copy, Please visit Library.}________*** Quantitative Analysis Upper-Division Undergraduate Analytical Chemistry Lasers Mass Spectrometry 540.7 0021-9584 RIEBPL Library https://pubs.acs.org/doi/epdf/10.1021/acs.jchemed.2c01111 https://pubs.acs.org/doi/epdf/10.1021/acs.jchemed.2c01111 231020 20231020161118.0