Incorporation of a Virtual Proteomics Module into the Undergraduate Analytical Curriculum (Record no. 44896)
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| fixed length control field | 02874nam a22002777a 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20231116122839.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 231020b ||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| ISSN | 0021-9584 |
| 037 ## - SOURCE OF ACQUISITION | |
| Source of stock number/acquisition | RIEBPL Library |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 540.7 |
| 100 ## - MAIN ENTRY--AUTHOR NAME | |
| Personal name | Kathryn L. Kapp et al... |
| 245 ## - TITLE STATEMENT | |
| Title | Incorporation of a Virtual Proteomics Module into the Undergraduate Analytical Curriculum |
| Remainder of title | (Journal Article) |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication | USA |
| Name of publisher | :American Chemical Society |
| Year of publication | August 2023 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Number of Pages | 3124-3131 P. |
| 490 ## - SERIES STATEMENT | |
| Series statement | American Chemical Society, Volume 100, Issue 8 |
| 505 ## - FORMATTED CONTENTS NOTE | |
| Formatted contents note | ***______{For Hard Copy, Please visit Library.}________*** |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | Abstract<br/> <br/>Proteomics, or the study of the set of proteins in an organism, tissue, or cell, is a rapidly growing field within bioanalytical chemistry that can be used to investigate many biological questions. However, proteomics is not fully integrated into the undergraduate chemistry curriculum because of a lack of access to expertise, the cost of required analytical instrumentation (liquid chromatography [LC] and mass spectrometry [MS]), and the time required for proteomics experiments. A virtual proteomics module was developed for flexible learning environments (i.e., in-person, hybrid, online) to introduce undergraduate Analytical Chemistry students to proteomics without the need for expensive instrumentation. This module teaches students about proteomics sample preparation and data acquisition, provides real LC-MS/MS data from unknown plasma samples for students to analyze, and provides experience with Mascot, a free online data analysis platform that can be used to identify the species of origin. The module was implemented in Introduction to Analytical Chemistry in two ways: (1) as a laboratory (online; ∼120 min) and (2) as a lecture (hybrid; ∼75 min). Students reported improved knowledge of proteomics after exposure to this module with average quiz scores increasing from 27% to 73%. In the lecture implementation, >90% of students successfully identified their unknowns, with almost 80% correctly justifying their conclusions. Additionally, students demonstrated increased interest in proteomics by formulating more complex research questions on the post-quiz (average of 40 words) than the pre-quiz (average of 18 words). This module was effective for students across majors and years and is a valuable educational tool that incorporates proteomics into the undergraduate chemistry curriculum across learning environments.<br/><br/> |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Upper-Division Undergraduate |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Analytical Chemistry Biochemistry |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Web-Based Learning Multimedia-Based |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Learning Bioanalytical Chemistry |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | HPLC Instrumental Methods Mass |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Spectrometry Proteins/PeptidesLearningz |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | https://doi.org/10.1021/acs.jchemed.3c00067 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Periodicals |
| Lost status | Damaged status | Home library | Current library | Date acquired | Full call number | Koha item type |
|---|---|---|---|---|---|---|
| RIE BPL Library | RIE BPL Library | 16.11.2023 | 540.7 | Periodicals |